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Related Concept Videos

Atypical Pneumonia01:14

Atypical Pneumonia

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Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease...
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Pneumonia IV: Management01:28

Pneumonia IV: Management

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The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
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Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pneumonia I: Introduction01:29

Pneumonia I: Introduction

17
Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
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Pneumonia I: Introduction01:30

Pneumonia I: Introduction

1.4K
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
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Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

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Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
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Related Experiment Video

Updated: Apr 22, 2026

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii
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A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

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[Therapy-resistant pneumonia].

Andreas Oestmann1, Stephan Christian Schäfer2, Thomas Geiser3

  • 1Universitätsklinik für Allgemeine Innere Medizin, Inselspital, Universitätsspital Bern.

Praxis
|October 12, 2014
PubMed
Summary
This summary is machine-generated.

A 72-year-old patient with B-symptoms and persistent pulmonary infiltrates improved with steroids, suggesting cryptogenic organizing pneumonia. This diagnosis was favored over secondary causes despite chronic lymphocytic leukemia.

Keywords:
KortikosteroideKryptogen organisierende PneumonieMasson-Körperchenbuds of granulation tissue (Masson-bodies)chronic lymphocytic leukemiachronisch-lymphatische Leukämiecorticoid steroidscryptogenic organizing pneumonia

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Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa
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A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii
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Methods for Detecting Cytotoxic Amyloids Following Infection of Pulmonary Endothelial Cells by Pseudomonas aeruginosa
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Area of Science:

  • Pulmonology
  • Internal Medicine
  • Pathology

Background:

  • Presents a challenging case of a 72-year-old patient with persistent pulmonary infiltrates and B-symptoms unresponsive to antibiotics.
  • Highlights the diagnostic dilemma in differentiating secondary organizing pneumonia from cryptogenic organizing pneumonia.

Observation:

  • Transbronchial biopsy revealed granulation tissue, indicative of organizing pneumonia.
  • The patient experienced rapid improvement in symptoms and pulmonary infiltrates following corticosteroid therapy.

Findings:

  • Despite a history of chronic lymphocytic leukemia and recent pneumonia, cryptogenic organizing pneumonia was deemed the most likely diagnosis.
  • The therapeutic response to steroids strongly supported the diagnosis of organizing pneumonia.

Implications:

  • This case underscores the importance of considering cryptogenic organizing pneumonia in patients with unexplained pulmonary infiltrates and B-symptoms.
  • Early recognition and treatment with corticosteroids can lead to favorable outcomes in organizing pneumonia.
  • Highlights the need for thorough differential diagnosis in complex pulmonary cases.