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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
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[Stroke prevention after stroke in patients with atrial fibrillation: a case-based review]

Tibor Kovács1

  • 1Semmelweis Egyetem, Általános Orvostudományi Kar Neurológiai Klinika Budapest Balassa u. 6. 1083.

Orvosi Hetilap
|October 13, 2014
PubMed

Insights

Novel oral anticoagulants like dabigatran, rivaroxaban, and apixaban are increasingly used for preventing strokes in patients with non-valvular atrial fibrillation. This review covers their guidelines and clinical use for secondary stroke prevention.

Area of Science:

  • Cardiology
  • Neurology
  • Pharmacology

Context:

  • Non-valvular atrial fibrillation significantly increases the risk of embolic cerebral infarcts.
  • Vitamin K antagonists have been the traditional treatment, but novel oral anticoagulants (NOACs) are now widely used.
  • NOACs offer an alternative for secondary stroke prevention in this patient population.

Purpose:

  • To review the current guidelines and clinical applications of NOACs in secondary stroke prevention.
  • To discuss the use of dabigatran, rivaroxaban, and apixaban in managing non-valvular atrial fibrillation.
  • To address practical questions regarding NOACs through a hypothetical case report.

Summary:

  • This review focuses on the use of novel oral anticoagulants (NOACs) including dabigatran, rivaroxaban, and apixaban.
  • It examines their role in the secondary prevention of ischemic stroke in patients with non-valvular atrial fibrillation.
  • Guideline recommendations and practical considerations are discussed in the context of a case report.

Impact:

  • Provides clinicians with up-to-date information on NOACs for stroke prevention.
  • Aids in decision-making for secondary stroke prevention strategies in non-valvular atrial fibrillation.
  • Contributes to optimizing anticoagulation therapy and improving patient outcomes in stroke prevention.

Keywords:
apixabanatrial fibrillationdabigatranpitvarfibrillációrivaroxabanstrokewarfarin

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