Jove
Visualize
Contact Us

Related Experiment Videos

Repair of incisional hernia.

J P Houck1, E B Rypins, I J Sarfeh

  • 1Surgical Service, Veterans Administration, Long Beach, California.

Surgery, Gynecology & Obstetrics
|November 1, 1989
PubMed
Summary

Incisional hernia repair carries a significantly higher wound infection risk compared to other clean surgeries. Patients with prior wound infections face a greater risk of reinfection during incisional hernia repair.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Despite activation of EGF-receptor-ERK signaling pathway, epithelial proliferation is impaired in portal hypertensive gastric mucosa: relevance of MKP-1, c-fos, c-myc, and cyclin D1 expression.

Life sciences·2002
Same author

Defective mitogen-activated protein kinase (ERK2) signaling in gastric mucosa of portal hypertensive rats: potential therapeutic implications.

Hepatology (Baltimore, Md.)·2001
Same author

Gene therapy for gastric ulcers with single local injection of naked DNA encoding VEGF and angiopoietin-1.

Gastroenterology·2001
Same author

Portal hypertensive gastric mucosa has reduced activation of MAP kinase (ERK2) in response to alcohol injury: a key to impaired healing?

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2001
Same author

ATP-induced CA2+-signaling enhances rat gastric microvascular endothelial cell migration.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2001
Same author

Isolation and characterization of rat gastric microvascular endothelial cells as a model for studying gastric angiogenesis in vitro.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2001
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Surgical Infection
  • Hernia Repair Outcomes
  • Wound Healing

Background:

  • Wound infection is a primary driver of incisional hernia development.
  • The risk of surgical site infection after incisional hernia repair is not well-established.
  • Previous infections may impact subsequent surgical outcomes.

Purpose of the Study:

  • To determine if incisional hernia repair is associated with a higher incidence of wound infection.
  • To compare infection rates between incisional hernia repairs and other clean surgical procedures.
  • To identify risk factors for infection in incisional hernia repair.

Main Methods:

  • Retrospective analysis of 995 clean surgical procedures over 30 months.
  • Comparison of infection rates in 80 incisional hernia repairs versus 915 other clean procedures.
  • Analysis of infection rates based on prior wound infection history and antibiotic prophylaxis.

Main Results:

  • Incisional hernia repair had a 16% infection rate, significantly higher than other clean procedures (1.5%).
  • Patients with a history of wound infection had a 41% reinfection rate after incisional hernia repair.
  • Antibiotic prophylaxis showed a trend towards reduced infection rates (11% vs. 21%).

Conclusions:

  • Incisional hernia repair is not a clean surgical procedure due to its high infection rate.
  • Prior wound infection is a significant risk factor for reinfection during incisional hernia repair.
  • Perioperative antibiotic prophylaxis may be beneficial, warranting further randomized study.

Related Experiment Videos