Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Type II Diabetes II: Pathophysiology01:24

Type II Diabetes II: Pathophysiology

6
PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
6
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

5
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
5
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

4.8K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.8K
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

5
Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated...
5
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

10
Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the...
10
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

10.4K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
10.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microbiological and molecular identification of the anaerobic component of the oral microbiota in patients with cancer of the oropharyngeal region.

Klinicheskaia laboratornaia diagnostikaยท2022
Same author

[PITUITARY ADENOMA APOPLEXY].

Klinicheskaia meditsinaยท2018
Same author

[The concurrence of diabetes mellitus and gallstone disease].

Terapevticheskii arkhivยท2017
Same author

[Adiponectin in health and disease].

Terapevticheskii arkhivยท2017
Same author

[The ghrelin-obestatin system in health and disease].

Terapevticheskii arkhivยท2015
Same author

[Comparative analysis of the changing pattern of thyroid disease in patients with type 2 diabetes mellitus in the Perm region after 10 years].

Terapevticheskii arkhivยท2014

Related Experiment Video

Updated: Apr 22, 2026

Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise
05:06

Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise

Published on: July 14, 2023

2.6K

[Thyroid dysfunction in patients with type 2 diabetes mellitus].

I V Tereshchenko, A A Suslina

    Terapevticheskii Arkhiv
    |October 14, 2014
    PubMed
    Summary
    This summary is machine-generated.

    Annual screening for thyroid dysfunction is crucial for type 2 diabetes patients to prevent vascular events. This update covers concurrent diseases, atherogenesis, and therapy impacts.

    More Related Videos

    Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
    06:22

    Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model

    Published on: November 29, 2024

    1.6K
    Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
    07:30

    Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

    Published on: May 10, 2018

    8.2K

    Related Experiment Videos

    Last Updated: Apr 22, 2026

    Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise
    05:06

    Author Spotlight: Integrating Tai Chi with Mindfulness Training to Achieve an Effective Mind-Body Exercise

    Published on: July 14, 2023

    2.6K
    Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model
    06:22

    Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model

    Published on: November 29, 2024

    1.6K
    Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
    07:30

    Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion

    Published on: May 10, 2018

    8.2K

    Area of Science:

    • Endocrinology
    • Cardiovascular Medicine

    Context:

    • Type 2 diabetes mellitus (T2DM) frequently co-occurs with thyroid dysfunction.
    • This comorbidity is linked to increased risks of vascular events and atherogenesis.

    Purpose:

    • To provide an updated review on the interplay between T2DM and thyroid dysfunction.
    • To evaluate the impact of therapeutic interventions on the progression of both conditions and associated vascular complications.

    Summary:

    • The paper synthesizes current knowledge on the concurrent management of T2DM and thyroid disorders.
    • It highlights the role of thyroid dysfunction in accelerating vascular events and atherogenesis in diabetic patients.
    • Therapeutic strategies for managing both conditions are discussed in relation to their impact on disease course.

    Impact:

    • Emphasizes the need for routine annual thyroid screening in all individuals with T2DM.
    • Aims to improve clinical practice by promoting integrated management of these common endocrine disorders.
    • Contributes to reducing the burden of cardiovascular disease in the diabetic population.