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Nasal steroids in snorers can decrease snoring frequency: a randomized placebo-controlled crossover trial.

Ioannis Koutsourelakis1, Anastasios Keliris, Aliki Minaritzoglou

  • 1Center of Sleep Disorders, A' Department of Critical Care and Pulmonary Services, Evangelismos Hospital, Medical School of Athens University, Athens, Greece.

Journal of Sleep Research
|October 14, 2014
PubMed
Summary
This summary is machine-generated.

Nasal budesonide treatment in snorers increased nasal breathing and reduced snoring frequency. This study shows nasal steroids can improve breathing patterns and decrease snoring indices.

Keywords:
sleep-disordered breathing

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Area of Science:

  • Otorhinolaryngology
  • Sleep Medicine
  • Pharmacology

Background:

  • Nasal obstruction is anecdotally linked to snoring.
  • The efficacy of nasal steroids in altering breathing patterns and reducing snoring is not well-established.

Purpose of the Study:

  • To evaluate the effect of nasal budesonide on breathing route patterns and snoring indices in adult snorers.
  • To determine if nasal steroid application can increase nasal breathing and decrease oral/oro-nasal breathing, thereby reducing snoring.

Main Methods:

  • A randomized, double-blind, crossover trial involving 24 snorers.
  • Participants received 1-week of nasal budesonide or placebo, with crossover after a washout period.
  • Nasal resistance, breathing route patterns, and snoring were assessed via polysomnography.

Main Results:

  • Nasal budesonide significantly increased nasal breathing epochs and decreased oral/oro-nasal breathing.
  • Snoring frequency decreased by 15.8% with budesonide, and rapid eye movement (REM) sleep increased.
  • Snoring intensity reduction was observed primarily in patients with elevated baseline nasal resistance.

Conclusions:

  • Nasal budesonide can enhance nasal breathing and modestly reduce snoring frequency in snorers.
  • The findings suggest a potential therapeutic role for nasal steroids in managing snoring related to nasal obstruction.
  • Increased nasal breathing was inversely correlated with reduced snoring frequency.