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[Performance of a standardized interrogation to improve the screening of Chlamydia trachomatis infection]
S Grandcolin1, A de Hauteclocque2, A Lafoscade3
1Service de gynécologie-obstétrique, département de médecine générale, CHU de Poitiers / faculté de médecine et de pharmacie, université de Poitiers, 2, rue de la Milétrie, 86021 Poitiers, France.
Aim:
To estimate the performance of a standardized interrogation tool facilitating the detection and screening of patients for the Chlamydia trachomatis infection, to estimate the prevalence of the infection in the family planning population studied.
Method:
Prospective observational study, including the patients who had a consultation in the abortion center in the CHU of Poitiers. A sampling of the cervix was systematically carried out after the standardized interrogation in search of four clinical signs. The samples were analyzed by genetic amplification.
Results:
Three hundred and eighty-six women were included and 56 (14.5 %) infections were identified. The medical history questionnaire was relatively effective for 2 or 3 clinical signs. The positive predictive value (PPV) was respectively 34.8 % and 53.8 % and was very relevant for 4 clinical signs with PPV at 83.3 % [CI 95 %: 74-93 %]. Among the infected women, 48.2 % had no clinical sign revealed by the medical history questionnaire. The presence of any clinical sign was strongly associated with the C. trachomatis infection (P<0.05).
Conclusion:
The clinical signs find in the standardized interrogation are all significantly associated with the C. trachomatis infection.
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