Related Experiment Video
Updated: Apr 22, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
A rare case of multinodular pulmonary amyloidosis
Jizhen Feng1, Jiamei Li2, Chunxiang Ling1
1Department of Radiology, Shandong Provincial Hospital affiliated to Shandong University, Jinan, China.
Background And Aims:
Pulmonary amyloidosis is usually associated with systemic amyloidosis. Localized pulmonary amyloidosis without systemic amyloidosis is even rare. We reported a rare case of multinodular pulmonary amyloidosis to improve the understanding of the disease.
Methods:
Report of a case.
Results:
We present an unusual case of primary pulmonary multinodular amyloidosis in a middle-aged woman. She presented our hospital with cough and chest distress only. Results of computed tomography (CT) showed multiple nodules with diffused calcification and thick-walled cavity in bilateral lung parenchyma. And the diagnosis of nodular amyloidosis was established by a CT-guided core needle biopsy.
Conclusions:
The case clearly shows it is difficult to distinguish parenchymal nodular amyloidosis from malignant primary lung neoplasm in radiology because of their similar images. Thus, the role of CT-guided core needle biopsy in diagnosis of pulmonary multinodular amyloidosis is very important.
Related Concept Videos
Amyloid Fibrils
Amyloid Fibrils
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
Chronic Obstructive Pulmonary Disease II: Emphysema
Atypical Pneumonia
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:

