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Updated: Apr 22, 2026

Syntheses, Crystallization, and Spectroscopic Characterization of 3,5-Lutidine N-Oxide Dehydrate
Published on: April 24, 2018
Crystal structure of 4-(prop-2-yn-yloxy)-2,2,6,6-tetra-methyl-piperidin-1-ox-yl
Shailesh K Goswami1, Lyall R Hanton1, C John McAdam1
1Department of Chemistry, University of Otago, PO Box 56, Dunedin, New Zealand.
Abstract:
The title compound, C12H20NO2, was synthesized from 4-hy-droxy-2,2,6,6-tetra-methyl-piperidin-1-oxyl (hy-droxy-TEMPO) and propargyl bromide. The six-membered ring adopts a flattened chair conformation and carries a propyn-yloxy substituent in an equatorial orientation at the 4-position. The N-O bond length of the piperidin-1-oxyl unit is 1.289 (3) Å. In the crystal, C-H⋯O hydrogen bonds combine with unusual C-H⋯π inter-actions involving the alkyne unit as acceptor to generate a three-dimensional network.
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