Related Experiment Video
Updated: Apr 22, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Prevalence of anxiety symptoms and depression in the third gestational trimester
Caroline Ronchini Ferreira1, Mayara Carolina Orsini, Camilla Ribeiro Vieira
1Faculdade de Nutrição, Universidade Federal de Alfenas (UNIFAL-MG), Rua Gabriel Monteiro da Silva, 700, Alfenas, MG, 37130-000, Brazil, carolronchini@yahoo.com.br.
Objective:
To determine the prevalence of anxiety and gestational depression and to determine the risk factors associated to its development.
Method:
Pregnant women during their third quarter of pregnancy were invited to participate to the study, and they signed an informed consent form. After that, they filled in a general assessment questionnaire in which socio-economical and obstetrical characteristics together with general health conditions and behaviors harmful for the pregnancy were evaluated. To determine the anxiety symptoms a STAI A-trait scale and a STAI-A-state scale were used and to measure the depression a CES-D scale was used. A data logistic regression was realized to determine significant associations. The significance level adopted was 0.05 for all statistical tests.
Results:
The final sample was represented by 207 pregnant women and the prevalence of depression was the highest value (73.5%), followed by state anxiety (58.5%) and finally by trait anxiety (53.2%). Only trait anxiety was explained by the variables studied and it was associated to the realization of a treatment for chronic diseases (OR = 2.93; IC = 1.02-8.41; p = 0.045) and the usage of continuous prescription drugs (OR = 2.30; IC = 1.06-4.97; p = 0.034).
Conclusions:
The prevalence of anxiety and depression among pregnant women were both high and only trait anxiety was explained by treatment for chronic diseases and the usage of continuous prescription drugs.
Related Concept Videos
Generalized Anxiety Disorder
Depression: Overview
Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depressive Disorders: MDD and Dysthymia

