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A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

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Brief interventions to reduce Ecstasy use: a multi-site randomized controlled trial.

Melissa M Norberg¹, Leanne Hides², Jake Olivier³

¹Centre for Emotional Health, Department of Psychology, Macquarie University; National Cannabis Prevention and Information Centre, UNSW Medicine, Sydney; National Drug and Alcohol Research Centre, UNSW Medicine, Sydney.

Behavior Therapy

|October 15, 2014

Summary

Motivational enhancement therapy (MET) did not significantly outperform education alone in reducing ecstasy use or related problems. However, participants receiving MET reported higher satisfaction, indicating potential benefits beyond direct outcome measures for ecstasy users.

Keywords:

MDMA ecstacy education motivational enhancement therapy randomized controlled trial

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Area of Science:

Addiction research
Psychological interventions
Public health

Background:

Motivational enhancement therapy (MET) effectiveness in augmenting ecstasy user education is unclear.
Previous studies lacked examination of treatment fidelity's impact on ecstasy use outcomes.

Purpose of the Study:

To compare a single-session MET with education-only for reducing ecstasy use and related problems.
To assess if higher MET treatment fidelity correlates with better outcomes.
To evaluate participant satisfaction with both interventions.

Main Methods:

A multi-site, parallel, two-group randomized controlled trial with 174 ecstasy users.
Interventions: 15-minute education vs. 50-minute MET (including education).
Outcomes assessed at baseline and 4, 16, 24 weeks; satisfaction at 4 weeks.

Main Results:

No significant group differences in ecstasy use, related problems, or commitment to change at 24 weeks.
Both groups showed ~50% reduction in ecstasy use and ~20% in problem severity.
MET participants reported slightly higher satisfaction; fidelity was not linked to outcomes.

Conclusions:

Single-session MET and education-only interventions yielded similar reductions in ecstasy use and problems.
MET may enhance participant satisfaction, suggesting potential indirect benefits.
Future research should explore mechanisms of change to improve interventions for ecstasy users.