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Updated: Apr 22, 2026
Synthesis of an Intein-mediated Artificial Protein Hydrogel
Published on: January 27, 2014
Programmable protein-DNA hybrid hydrogels for the immobilization and release of functional proteins
Yuzhou Wu1, Chuang Li, Felix Boldt
1Institute of Organic Chemistry III, Macromolecular Chemistry and Biomaterials, University of Ulm, Albert-Einstein-Allee 11, D-89081 Ulm, Germany. yuzhou.wu@uni-ulm.de tanja.weil@uni-ulm.de.
Abstract:
A modular approach for the precise assembly of multi-component hydrogels consisting of protein and DNA building blocks is described for the first time. Multi-arm DNA is designed for crosslinking and stepwise, non-covalent assembly of active proteins inside the hydrogel.
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