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Isolated, pupil-sparing third nerve palsy as initial manifestation of systemic lupus erythematosus
E D Rosenstein1, J Sobelman, N Kramer
1Division of Rheumatology, UMDNJ-New Jersey Medical Center, Newark.
Abstract:
A 29-year-old woman had an isolated, pupil-sparing third cranial nerve palsy. Serologic and CSF abnormalities and the subsequent course were consistent with systemic lupus erythematosus. Corticosteroid therapy resulted in improvement of ocular palsy within 4 weeks. The pathogenesis of cranial neuropathy in systemic lupus erythematosus and the unique presentation in this patient are discussed.