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Updated: Apr 22, 2026
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Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens
Published on: December 9, 2022
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[Pseudomyxoma peritonei. Two-case-report]
Ixchel Carranza-Martínez1, Gilberto Cornejo-López1, Montserrat Monroy-Argumedo1
1Cirugía General, Hospital Ángeles del Pedregal, México DF, Mexico.
Cirugia Y Cirujanos
|October 15, 2014
Summary
Pseudomyxoma peritonei is a rare condition of widespread abdominal mucinous tumors, often originating from the appendix. Diagnosis can be challenging, requiring surgical intervention and histopathology for confirmation.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Pseudomyxoma peritonei involves intraperitoneal dissemination of adenomucinous tumor cells.
- The cecal appendix is the most frequent primary origin for this condition.
Observation:
- Two cases are presented: a 74-year-old female with acute abdominal pain and a 73-year-old male with chronic abdominal discomfort.
- Initial diagnoses included acute appendicitis and abdominal mass, respectively.
- Surgical exploration revealed extensive, scattered mucinous tumor implants throughout the peritoneal cavity.
Findings:
- Histopathological examination confirmed pseudomyxoma peritonei in both patients.
- The disease is characterized by mucinous ascites and peritoneal tumor seeding.
- Diagnosis is often made during surgical procedures due to its rarity and complex presentation.
Implications:
- Pseudomyxoma peritonei is a rare malignancy with challenging diagnosis and characteristic mucinous ascites.
- The standard treatment involves cytoreductive surgery combined with perioperative and/or adjuvant chemotherapy.
