Related Experiment Video
Updated: Apr 22, 2026

Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
Published on: December 9, 2022
[Procalcitonin as a marker of intra-abdominal infection]
Elías Domínguez-Comesaña1, Julio Roberto Ballinas-Miranda2
1Servicio de cirugía, Complejo Hospitalario de Pontevedra, Pontevedra, Spain. eliasdomcom@gmail.com.
Background:
Procalcitonin is a quite specific biomarker of infection and in recent years has shown its superiority to others markers of inflammation, such as C-reactive protein, for the diagnosis and monitoring of a variety of infections.
Aim:
For this reason, several researchers have studied the potential role of procalcitonin for diagnosis and management of these infections.
Discussion:
Intra-abdominal infections are a heterogeneous group of infections that, sometimes, pose difficult challenges to physicians. The published studies have produced mixed results, leading to controversy on the utility of this marker in intra-abdominal infections.
Conclusions:
This review summarizes these data and discuss the utility of procalcitonin in several intra abdominal infections, including postoperative infections.
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