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Updated: Apr 22, 2026

Excitation-Scanning Hyperspectral Imaging Microscopy to Efficiently Discriminate Fluorescence Signals
Published on: August 22, 2019
Blind and fully constrained unmixing of hyperspectral images
Abstract:
This paper addresses the problem of blind and fully constrained unmixing of hyperspectral images. Unmixing is performed without the use of any dictionary, and assumes that the number of constituent materials in the scene and their spectral signatures are unknown. The estimated abundances satisfy the desired sum-to-one and nonnegativity constraints. Two models with increasing complexity are developed to achieve this challenging task, depending on how noise interacts with hyperspectral data. The first one leads to a convex optimization problem and is solved with the alternating direction method of multipliers. The second one accounts for signal-dependent noise and is addressed with a reweighted least squares algorithm. Experiments on synthetic and real data demonstrate the effectiveness of our approach.
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