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Eosinophilic cystitis: three cases, and a review over 10 years
Karina Sif Søndergaard Mosholt1, Claus Dahl1, Nessn Htum Azawi1
1Urological Department, Roskilde Hospital, Roskilde, Denmark.
BMJ Case Reports
|October 15, 2014
Summary
Eosinophilic cystitis (EC) is a rare bladder condition. Steroids, particularly tapered prednisone with antihistamines, show promise in managing EC symptoms and preventing recurrence.
Area of Science:
- Urology
- Pathology
- Immunology
Background:
- Eosinophilic cystitis (EC) is an uncommon inflammatory bladder condition.
- Understanding EC's causes, symptoms, and treatments is crucial for patient care.
Observation:
- Reviewed 56 EC cases over 10 years to identify patterns.
- Common symptoms include frequency, dysuria, urgency, pain, and hematuria.
- Key findings: bladder mass, peripheral eosinophilia, and thickened bladder wall.
Findings:
- Steroids, antibiotics, and antihistamines are frequently used treatments.
- Recurrence is noted when steroid treatment is reduced or stopped.
- No definitive treatment consensus exists for EC.
Implications:
- Tapered prednisone over 6-8 weeks combined with antihistamines is proposed as a preferred treatment.
- Further research is needed to establish standardized EC management protocols.
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