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Synthetic studies towards Zetekitoxin AB: preparation of 4,5-epi-11-hydroxy-saxitoxinol
Aaron D Pearson1, Robert M Williams1
1Department of Chemistry, Colorado State University, Fort Collins, CO 80523, USA.
Tetrahedron
|October 15, 2014
Abstract:
A concise synthesis of 4,5-epi-11-hydroxy-saxitoxinol utilizing D-ribose to direct an asymmetric Mannich reaction. This approach allows many modes of reactivity, which can be used to access various analogs of saxitoxin.

