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Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists

Stefan Peukert1, Richard Hughes1, Jill Nunez1

  • 1Novartis Institutes for BioMedical Research , 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.

ACS Medicinal Chemistry Letters
|October 15, 2014
PubMed

Keywords:
GLP-1 secretionGPR39 agonistsGPR39 receptorZn2+-sensing receptorantidiabetic treatmentinsulin secretionβ-cell protection

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