Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

5.9K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
5.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Resolution OCT of Presumed Basal Laminar Deposit and Retinal Pigment Epithelium Abnormalities in Extensive Macular Atrophy with Pseudodrusen-Like Appearance.

Ophthalmology. Retina·2026
Same author

Enhancing Detection and Diagnosis of Intraocular Lymphoma Through Advanced Retinal Imaging.

Clinical & experimental ophthalmology·2026
Same author

Choroideremia Carrier with Geographic Pattern and Peripapillary Involvement.

Retina (Philadelphia, Pa.)·2026
Same author

Intraretinal hyperreflective foci: Pathophysiology, imaging features, and clinical implications across retinal diseases.

Progress in retinal and eye research·2026
Same author

Imaging Measures for the Assessment of Disease Activity in Noninfectious Posterior Uveitis - Multimodal Imaging in Uveitis (MUV) Taskforce: Report 10.

American journal of ophthalmology·2026
Same author

REPLY.

Ophthalmology·2026

Related Experiment Video

Updated: Apr 22, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

468

Extreme choroidal thinning in high myopia.

Claudine E Pang1, David Sarraf, K Bailey Freund

  • 1*Vitreous-Retina-Macula Consultants of New York, New York, New York; †LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear and Throat Hospital, New York, New York; ‡Retinal Disorders and Ophthalmic Genetics Division, Jules Stein Eye Institute, University of California, Los Angeles, California; §Greater Los Angeles VA Healthcare Center, Los Angeles, California; and ¶Department of Ophthalmology, New York University School of Medicine, New York, New York.

Retina (Philadelphia, Pa.)
|October 15, 2014
PubMed
Summary

Extreme choroidal thinning in myopia is compatible with good visual acuity. This condition, identified via spectral domain optical coherence tomography, does not necessarily indicate a decline in vision over time.

More Related Videos

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

846
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

8.4K

Related Experiment Videos

Last Updated: Apr 22, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

468
Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

846
Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

8.4K

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Diseases

Background:

  • High myopia is associated with various ocular complications.
  • Choroidal thinning is a common finding in highly myopic eyes.
  • The functional implications of extreme choroidal thinning are not fully understood.

Purpose of the Study:

  • To characterize spectral domain optical coherence tomography findings in extreme choroidal thinning.
  • To assess the relationship between extreme choroidal thinning and visual acuity.
  • To evaluate the progression of extreme choroidal thinning over time.

Main Methods:

  • Retrospective observational case review of myopic patients with extreme choroidal thinning (subfoveal choroidal thickness ≤ 20 μm).
  • Analysis of spectral domain optical coherence tomography data, including choroidal and retinal thicknesses.
  • Assessment of clinical features such as visual acuity and axial length.

Main Results:

  • Thirty-six eyes with extreme choroidal thinning were analyzed (mean subfoveal choroidal thickness 13.9 ± 6.0 μm).
  • 70% of eyes (25/36) achieved visual acuity of 20/40 or better.
  • Eyes with poorer visual acuity often showed choroidal neovascularization or atrophy; no significant thinning progression was observed over a mean follow-up of 44.7 months.

Conclusions:

  • Extreme choroidal thinning in myopia can be compatible with good visual acuity.
  • Choroidal thickness alone is not a reliable predictor of visual function in myopic eyes.
  • This condition can be stable over extended follow-up periods, suggesting it may not be a direct indicator of visual impairment.