Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gallbladder01:17

Gallbladder

3.1K
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
3.1K
Cholecystitis01:20

Cholecystitis

20
Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
20
Appendicitis01:19

Appendicitis

18
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
18
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

7.1K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
7.1K
Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

3.3K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
3.3K
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

2.0K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cerebrospinal delivery of a bidirectional AAV9 vector improves optic nerve and retinal pathology in a sheep model of Tay-Sachs disease.

Molecular therapy : the journal of the American Society of Gene Therapy·2026
Same author

Routine Orogastric Tube Placement Reveals an Unexpected Diagnosis Resulting in a Change in Therapy: A Case Report.

Cureus·2026
Same author

Paediatric difficult intubations and the impact of timing of weekend versus weekday cases. Response to Br J Anaesth 2026; 136: 365-6.

British journal of anaesthesia·2026
Same author

TAZ (<i>Wwtr1</i>) deficiency leads to ER stress and mitochondrial dysfunction in a mouse model of Fuchs' endothelial corneal dystrophy.

bioRxiv : the preprint server for biology·2026
Same author

The role of epithelial membrane-associated mucin 4 in ocular surface health and corneal wound healing.

Frontiers in medicine·2026
Same author

Circulating Viral Antigenic Proteins and Inflammatory Biomarkers in Influenza and Respiratory Syncytial Virus Infections: Associations With Disease Severity and Transmission.

Cureus·2026

Related Experiment Video

Updated: Apr 22, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

10.6K

Gall bladder lymphoid hyperplasia: masquerading as lymphoma.

Safia Rana, Zeeba S Jairajpuri, Sabina Khan

  • 1Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, Hamdard Nagar, New Delhi, India.

Journal of Cancer Research and Therapeutics
|October 15, 2014
PubMed
Summary

Reactive lymphoid hyperplasia of the gallbladder is a rare condition that can mimic lymphoma on histopathology. This case highlights the importance of biopsy for accurate diagnosis in gallbladder pathology.

More Related Videos

Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin
09:10

Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin

Published on: December 16, 2013

5.3K
Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

6.1K

Related Experiment Videos

Last Updated: Apr 22, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
10:52

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma

Published on: March 30, 2018

10.6K
Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin
09:10

Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin

Published on: December 16, 2013

5.3K
Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

6.1K

Area of Science:

  • Gastroenterology
  • Surgical Pathology
  • Oncologic Pathology

Background:

  • Lymphoid hyperplasia of the gallbladder is an exceedingly rare entity.
  • It can present diagnostic challenges, potentially mimicking malignant conditions like lymphoma on histopathology.
  • Accurate diagnosis relies heavily on histopathological examination.

Discussion:

  • This case report details a 58-year-old male with abdominal pain, initially evaluated for chronic cholecystitis and cholelithiasis.
  • Laparoscopic cholecystectomy revealed reactive lymphoid hyperplasia, characterized by diffuse lymphoid follicles and sheets of lymphoid cells within the gallbladder wall.
  • The findings underscore the importance of distinguishing reactive hyperplasia from neoplastic processes in gallbladder pathology.

Key Insights:

  • Reactive lymphoid hyperplasia of the gallbladder can histopathologically resemble lymphoma.
  • Microscopic evaluation is crucial for differentiating benign reactive changes from malignancies.
  • Gallbladder biopsies are essential for definitive diagnosis in ambiguous cases.

Outlook:

  • Further research into the specific triggers and pathogenesis of gallbladder lymphoid hyperplasia may improve diagnostic algorithms.
  • Enhanced awareness among pathologists and clinicians can reduce misdiagnosis rates.
  • Continued reporting of rare gallbladder pathologies contributes to a comprehensive understanding of differential diagnoses.