An overview of disparities and interventions in pediatric kidney transplantation worldwide

Michael A Freeman1, Larissa Myaskovsky

  • 1Division of Pediatric Nephrology and Hypertension, Penn State Hershey Children's Hospital, Mail Code H085, 500 University Drive, Hershey, PA, 17033, USA, MFreeman3@hmc.psu.edu.

Insights

Racial disparities persist in pediatric kidney transplantation globally, affecting both living and deceased donor transplants. Multifactorial patient and provider barriers contribute to these inequities, necessitating targeted interventions.

Area of Science:

  • Pediatric Nephrology
  • Transplantation Science
  • Health Equity Research

Background:

  • Persistent racial disparities exist in pediatric kidney transplantation worldwide.
  • These inequities are observed in both living and deceased donor contexts.
  • Disparities are independent of clinical factors between racial groups.

Purpose of the Study:

  • To review current findings on racial disparities in pediatric kidney transplantation.
  • To examine multifactorial patient and provider barriers contributing to these disparities.
  • To consider potential interventions for reducing these inequities.

Main Methods:

  • Literature review of current research on pediatric kidney transplant disparities.
  • Analysis of factors influencing access and outcomes in pediatric kidney transplantation.
  • Synthesis of evidence on patient and provider barriers.

Main Results:

  • Racial disparities in pediatric kidney transplantation are well-documented globally.
  • Both patient-level and provider-level factors contribute significantly to these disparities.
  • Existing organ allocation systems have not eliminated these inequities.

Conclusions:

  • Addressing racial disparities in pediatric kidney transplantation requires a multifaceted approach.
  • Interventions must target both patient-related and provider-related barriers.
  • Further research and policy changes are needed to promote equitable access to transplantation.

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