[Detection of T-lymphocytes in human endometrium]

The T cell subpopulations in normal human endometrium were investigated by the immunoperoxidase technique with monoclonal antibodies. The total number of 100 endometrial biopsies from different phases of menstrual cycle were analyzed. It could be established, that the number of T cells shows typical variations during the cycle. The T suppressor cells increase in the ovulation and late luteal phase and decrease in the early luteal phase. The T helper cells were rare and without typical changes. It is assumed, that the regulation of T cells in the endometrium is connected with the formation of an optimal environment for the immigration of sperms and the implantation of the blastocyst.