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Related Concept Videos

Type I Diabetes I: Introduction01:12

Type I Diabetes I: Introduction

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Type 1 diabetes mellitus is a chronic metabolic disorder characterized by an absolute deficiency of insulin resulting from the autoimmune destruction of pancreatic β-cells. Although it can occur at any age, it is most commonly diagnosed in childhood, adolescence, or early adulthood. The loss of insulin production impairs cellular glucose uptake, resulting in persistent hyperglycemia and necessitating lifelong insulin therapy.Autoimmune Destruction of β-CellsThe hallmark of type 1...
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Type II Diabetes I: Introduction01:26

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Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
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Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Diabetes Mellitus: Introduction01:26

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Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and...
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Diabetic Retinopathy01:27

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
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Type I Diabetes II: Pathophysiology01:26

Type I Diabetes II: Pathophysiology

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Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular...
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Updated: Apr 22, 2026

Isolation of Human Islets from Partially Pancreatectomized Patients
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InDependent Diabetes Trust.

Roger Evans1

  • 1Nursing Standard.

Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
|October 16, 2014
PubMed
Summary

The InDependent Diabetes Trust (IDDT) is a UK charity established in 1994 by and for individuals with diabetes. It operates solely on voluntary donations, ensuring independence from pharmaceutical funding.

Area of Science:

  • Diabetes Management
  • Charitable Organizations
  • Patient Advocacy

Background:

  • The InDependent Diabetes Trust (IDDT) was founded in 1994.
  • It is a UK-based registered charity.
  • The organization is run by individuals with diabetes for the benefit of others with the condition.

Purpose of the Study:

  • To provide support and resources for people living with diabetes.
  • To maintain operational independence through voluntary donations.
  • To avoid conflicts of interest by not accepting pharmaceutical funding.

Main Methods:

  • The charity operates on a voluntary basis.
  • Funding is derived exclusively from public donations.
  • No financial contributions are accepted from pharmaceutical companies.

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Main Results:

  • The IDDT has been providing support since 1994.
  • The organization maintains its independence.
  • Financial sustainability is achieved through voluntary donations.

Conclusions:

  • The InDependent Diabetes Trust (IDDT) is a self-sustaining charity.
  • Patient-led support for diabetes is effectively delivered.
  • Independence from industry funding ensures unbiased support for diabetes patients.