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Related Concept Videos

Continuous Renal Replacement Therapy01:30

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Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
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Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

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Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
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Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

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Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Kidney Transplant II: Surgical Procedure01:26

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Related Experiment Video

Updated: Apr 22, 2026

Modeling Hypoxia/Reoxygenation Injury in Proximal Tubular Epithelial Cells
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[Renal replacement therapy in the intensive care unit].

M P Woznowski1, L C Rump, G Schieren

  • 1Klinik für Nephrologie, Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.

Der Internist
|October 16, 2014
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Summary

Acute kidney injury (AKI) is a common complication in critically ill patients, impacting survival. Early diagnosis, prophylactic measures, and individualized renal replacement therapy are crucial for modern intensive care.

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Area of Science:

  • Nephrology
  • Intensive Care Medicine
  • Critical Care

Context:

  • Acute kidney injury (AKI) is a frequent and severe complication in critically ill patients.
  • AKI significantly increases mortality rates and affects long-term patient prognosis.
  • Even minor alterations in renal function have profound clinical implications.

Purpose:

  • To review the key aspects of prophylaxis and early diagnosis of AKI.
  • To summarize various treatment modalities for renal replacement therapy (RRT) in intensive care settings.
  • To emphasize the importance of individualized RRT for critically ill patients with renal failure.

Summary:

  • This review focuses on the prophylaxis, early detection, and management of AKI in intensive care units.
  • It highlights the necessity of proactive strategies and timely interventions.
  • The discussion encompasses diverse RRT options tailored to individual patient needs.

Impact:

  • Provides a comprehensive overview of current approaches to AKI management in critical care.
  • Underscores the significance of personalized RRT for improving patient outcomes.
  • Aims to guide intensive care professionals in optimizing the treatment of critically ill patients with renal dysfunction.