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Frequency of bacteria causing urinary tract infections and their antimicrobial resistance patterns among pediatric

M Yasemi1, H Peyman1, K Asadollahi2

  • 1Student Research Committee, Ilam University of Medical Sciences Ilam, Iran.

Journal of Biological Regulators and Homeostatic Agents
|October 16, 2014
PubMed

Insights

Urinary Tract Infections (UTIs) in infants and neonates are common. E. coli is the most frequent cause, showing high resistance to common antibiotics like tetracycline and ampicillin.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Urinary Tract Infections (UTIs) are a significant health concern in infants and neonates.
  • Prompt diagnosis and appropriate treatment are crucial to prevent severe complications.

Purpose of the Study:

  • To determine the prevalence of bacterial pathogens causing UTIs in hospitalized infants and neonates.
  • To analyze the antimicrobial resistance patterns of these pathogens in Ilam province, Iran.

Main Methods:

  • A cross-sectional retrospective study was conducted on 220 infant and neonate UTI cases from 2007-2009.
  • Demographic and clinical data were collected via a standard checklist from health records.
  • Bacterial isolates were identified, and their antibiotic susceptibility was tested.

Main Results:

  • E. coli was the most common pathogen (44.5%), followed by Klebsiella spp. (18.6%), Enterobacter spp. (15%), and Staphylococcus spp. (12.7%).
  • High resistance rates were observed for tetracycline, ampicillin, and nalidixic acid.
  • Female infants constituted the majority of UTI cases (64.8%).

Conclusions:

  • E. coli is the predominant cause of UTIs in this pediatric population.
  • Significant antimicrobial resistance necessitates careful selection of antibiotics for effective UTI treatment in neonates and infants.
  • Antimicrobial sensitivity data are vital for guiding clinical decisions and reducing UTI-related complications.

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