Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Automated Microbial Diagnostics

Automated Microbial Diagnostics

Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

ChatGPT-polished writing boosts the risk of human-authored manuscripts being miscredited as AI-generated.

JAAD international·2025

Same author

Primary myelofibrosis with concurrent MPL and atypical JAK2 mutations.

Journal of hematopathology·2025

Same author

Adapting ChatGPT for Color Blindness in Medical Education.

Annals of biomedical engineering·2024

Same author

Inpatient Test Utilization and Test Volume Benchmarking: A Q-Probes Study.

Archives of pathology & laboratory medicine·2024

Same author

Red Blood Cell Transfusion Practices: College of American Pathologists Q-Probes Studies of Red Blood Cell Utilization and Single and Double Red Blood Cell Unit Transfusions.

Archives of pathology & laboratory medicine·2024

Same author

Archived Cytogenetic Cell Pellets Used to Detect a BCR::ABL1 Driver Mutation Eight Years before Disease Presentation.

Case reports in hematology·2024

Search research articles

Related Experiment Video

Updated: Apr 22, 2026

A Plasma Sample Preparation for Mass Spectrometry using an Automated Workstation

A Plasma Sample Preparation for Mass Spectrometry using an Automated Workstation

Published on: April 24, 2020

Workflow analysis comparing manual and automated specimen processing for mass spectrometry-based vitamin D testing.

Danyel Hermes Tacker¹, Joyce Topardo², Carole Mahaffey²

¹Clinical Laboratory, Department of Pathology, West Virginia University Hospital, Morgantown, West Virginia dtacker@hsc.wvu.edu.

Laboratory Medicine

|October 16, 2014

Summary

Automating specimen preparation significantly reduces preparation times and labor needs for mass spectrometry assays. This efficiency is most notable with larger batch sizes, freeing up technologist time.

Keywords:

automation cycle time full-time equivalent labor usage mass spectrometry specimen extraction workflow

More Related Videos

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry UPLC-HRMS

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry UPLC-HRMS

Published on: May 20, 2013

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization

Published on: February 27, 2020

Related Experiment Videos

Last Updated: Apr 22, 2026

A Plasma Sample Preparation for Mass Spectrometry using an Automated Workstation

A Plasma Sample Preparation for Mass Spectrometry using an Automated Workstation

Published on: April 24, 2020

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry UPLC-HRMS

Untargeted Metabolomics from Biological Sources Using Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry UPLC-HRMS

Published on: May 20, 2013

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization

Simultaneous Affinity Enrichment of Two Post-Translational Modifications for Quantification and Site Localization

Published on: February 27, 2020

Area of Science:

Clinical Chemistry
Laboratory Automation
Mass Spectrometry

Background:

Manual specimen preparation is time-consuming and labor-intensive.
Optimizing laboratory workflows is crucial for efficiency and cost-effectiveness.
Solid-phase extraction is a common method for specimen preparation.

Purpose of the Study:

To quantify the benefits of automating specimen extraction.
To compare manual and automated methods for specimen preparation time and labor usage.

Main Methods:

Workflow modeling and time-motion studies were employed.
Manual and automated (Tecan Freedom EVO 150) solid-phase extraction methods were compared.
20 batches (5-90 specimens each) were processed over 4 weeks; technologist fatigue was measured.

Main Results:

Automated preparation significantly reduced batch preparation time, per-specimen processing time, and labor requirements for all batch sizes.
Technologist fatigue became significant at batch sizes of 60 specimens.
Automated methods resulted in more uniform cycle times and provided up to 85 minutes of technologist idle time for 90-specimen batches.

Conclusions:

Automated specimen preparation offers substantial time and labor savings.
Automation should be considered for batch sizes of 35-40 specimens per day.
Robotic liquid-handling systems enhance laboratory efficiency and technologist well-being.