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Echocardiographic Assessment Using Subxiphoid-Only Examination for Hypotensive Patients
Published on: April 18, 2025
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Hypotension associated with advanced hodgkin lymphoma
Ankit Mangla1, Geetanjali Dang1, Hussein Hamad1
1Department of Internal Medicine, John H. Stroger Jr. Hospital of Cook County , Chicago, IL, USA.
Hematology Reports
|October 16, 2014
Summary
Hypotension is a rare symptom of Hodgkin lymphoma. This case highlights a patient with septic shock and liver lesions, ultimately diagnosed with Hodgkin lymphoma.
Area of Science:
- Oncology
- Hematology
- Internal Medicine
Background:
- Hypotension is an exceptionally rare clinical presentation of Hodgkin lymphoma.
- Septic shock is a critical condition requiring immediate medical intervention.
Observation:
- A patient presented with new-onset hypotension, diagnosed with urosepsis and septic shock.
- Abdominal CT revealed new liver lesions compared to a prior scan.
- Liver and bone marrow biopsies confirmed Hodgkin lymphoma with characteristic Reed-Sternberg cells (CD15+, CD30+).
Findings:
- The patient's hypotension was attributed to septic shock, with Hodgkin lymphoma as an underlying, rare cause.
- Immunohistochemical staining confirmed the diagnosis of Hodgkin lymphoma.
Implications:
- This case underscores the importance of considering rare diagnoses in patients with unusual presentations.
- The pathogenesis of hypotension in Hodgkin lymphoma may involve complex cytokine interactions and vasodilatory mediators, particularly in advanced stages.
- Further research is needed to elucidate the mechanisms linking Hodgkin lymphoma to hypotension.
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