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Effect of medication adherence on blood pressure control and risk factors for antihypertensive medication adherence

Zhao Yue1, Wang Bin, Qi Weilin

  • 1Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.

Journal of Evaluation in Clinical Practice
|October 17, 2014
PubMed

Insights

High rates of medication non-adherence are prevalent in Chinese hypertensive patients. Improving adherence involves addressing factors like drug use duration, antiplatelet use, cost concerns, professional guidance, and family support.

Area of Science:

  • Cardiovascular medicine
  • Public health
  • Pharmacology

Background:

  • Hypertension is a significant global health concern.
  • Medication adherence is crucial for effective blood pressure management.
  • Suboptimal adherence rates impact treatment outcomes in hypertensive populations.

Purpose of the Study:

  • To identify risk factors for medication non-adherence in Chinese hypertensive patients.
  • To examine the relationship between medication adherence and blood pressure control.
  • To inform targeted interventions for improving adherence.

Main Methods:

  • A cross-sectional study was conducted in Shanghai, China.
  • Data collected via validated scales, questionnaires, and medical records.
  • 232 Chinese hypertensive patients participated.

Main Results:

  • Over 50% of patients exhibited suboptimal adherence.
  • Adherence significantly correlated with better systolic blood pressure control.
  • Factors associated with higher adherence included longer drug use, antiplatelet co-medication, lower cost concerns, and greater professional/family support.

Conclusions:

  • A high prevalence of medication non-adherence exists among Chinese hypertensive patients.
  • Interventions targeting identified risk factors are needed.
  • Improving adherence can enhance blood pressure control in clinical practice.
Abstract

Keywords:
Chineseclinical outcomehypertensionmedication adherencerisk factorssocial support

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