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Methods of reducing fever

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:

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Related Experiment Video

Updated: Apr 22, 2026

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy

Published on: October 28, 2022

Transporting neonates with hypoxic-ischemic encephalopathy utilizing active hypothermia.

M D Weiss¹, A Tang², L Young³

¹Department of Pediatrics, University of Florida, Gainesville, FL, USA ShandsCair Flight Program, University of Florida, Gainesville, FL, USA.

Journal of Neonatal-Perinatal Medicine

|October 17, 2014

Summary

A servo-controlled active hypothermia device effectively cools neonates with hypoxic-ischemic encephalopathy (HIE) during transport. The device rapidly achieves and maintains target temperatures in ambulances, aircraft, and helicopters.

Keywords:

Active hypothermia encephalopathy hypoxic-ischemic neonates transport

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Last Updated: Apr 22, 2026

Early Pathological and Magnetic Resonance Detection of Cerebral Injury Using a Rat Model of Neonatal Hypoxic Ischemic Encephalopathy

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Published on: October 28, 2022

Author Spotlight: Assessing the Feasibility of Using Amplitude-Integrated EEG During Neonatal Transport

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Published on: June 21, 2024

The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia

The Hypoxic Ischemic Encephalopathy Model of Perinatal Ischemia

Published on: November 19, 2008

Area of Science:

Neonatal Intensive Care
Thermoregulation
Transport Medicine

Background:

Hypoxic-ischemic encephalopathy (HIE) is a serious condition in newborns.
Therapeutic hypothermia is a standard treatment for HIE.
Transporting neonates requiring therapeutic hypothermia presents unique challenges.

Purpose of the Study:

To evaluate a servo-controlled active hypothermia device for neonatal transport.
To assess the device's efficacy in achieving and maintaining target temperatures during transport.

Main Methods:

Retrospective review of neonates treated with therapeutic hypothermia (2009-2013).
Analysis of data from a servo-controlled active hypothermia device during ground and air transport.
Inclusion of 28 neonates with HIE.

Main Results:

The servo-controlled device successfully captured core temperatures in all 28 neonates.
All neonates reached target temperatures (33-34 °C) within 33 minutes.
Consistent target temperatures (33 ± 0.2 °C) were maintained throughout transport, irrespective of vehicle type.

Conclusions:

Servo-controlled hypothermia is effective for rapid temperature attainment and maintenance during neonatal transport.
The device ensures stable core temperatures in neonates with HIE during both ground and air transfers.
This technology facilitates optimal therapeutic hypothermia management for critically ill neonates on the move.