Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

X-ray Imaging01:24

X-ray Imaging

7.7K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
7.7K
X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

3.8K
X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal...
3.8K
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

678
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
678
Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

9.3K
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
9.3K
Scanning Electron Microscopy01:07

Scanning Electron Microscopy

5.1K
A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
Fundamental Principles
Accelerated...
5.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of concurrent colonic CMV infection on clinical outcomes in immune checkpoint inhibitor-induced colitis.

European journal of cancer (Oxford, England : 1990)·2026
Same author

Advances in Clinical Cardiology 2025: A Summary of Key Clinical Trials.

Advances in therapy·2026
Same author

Self-patterning hybrid membranes enable domain-specific immobilization of responsive nanoassemblies.

Journal of colloid and interface science·2026
Same author

Factors associated with contraceptive use among reproductive-age women during a pandemic: Evidence from a small developing state.

PLOS global public health·2026
Same author

Long-term cardiovascular function and cardiopulmonary performance in athletes after COVID-19: results from the COSMO study.

Frontiers in cardiovascular medicine·2026
Same author

Tunable Structural Color in Copolymer Microgels Through Controlled Synthesis and Thermally Induced Assembly.

Small science·2026

Related Experiment Video

Updated: Apr 22, 2026

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
07:48

High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

Published on: September 30, 2022

1.5K

Energy weighted x-ray dark-field imaging.

Georg Pelzer, Andrea Zang, Gisela Anton

    Optics Express
    |October 17, 2014
    PubMed
    Summary

    Enhancing x-ray dark-field imaging with energy-resolving pixel detectors improves microstructure visualization. This advancement in grating-based x-ray phase-contrast imaging (XPCi) boosts contrast-noise-ratio (CNR) and allows for reduced radiation dose.

    More Related Videos

    Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography
    10:18

    Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography

    Published on: February 21, 2017

    9.0K
    Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles
    10:00

    Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles

    Published on: July 5, 2016

    14.2K

    Related Experiment Videos

    Last Updated: Apr 22, 2026

    High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue
    07:48

    High Spatial Resolution Chemical Imaging of Implant-Associated Infections with X-ray Excited Luminescence Chemical Imaging Through Tissue

    Published on: September 30, 2022

    1.5K
    Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography
    10:18

    Dynamic Pore-scale Reservoir-condition Imaging of Reaction in Carbonates Using Synchrotron Fast Tomography

    Published on: February 21, 2017

    9.0K
    Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles
    10:00

    Energy Dispersive X-ray Tomography for 3D Elemental Mapping of Individual Nanoparticles

    Published on: July 5, 2016

    14.2K

    Area of Science:

    • Medical Imaging
    • X-ray Physics
    • Materials Science

    Background:

    • Grating-based x-ray phase-contrast imaging (XPCi) offers sub-pixel resolution for microstructures.
    • Dark-field images in XPCi are crucial for revealing fine details.
    • Improving dark-field image quality is essential for enhanced structural analysis.

    Purpose of the Study:

    • To demonstrate enhanced dark-field image quality using an energy-resolving pixel detector.
    • To investigate the impact of energy resolution on XPCi dark-field imaging.
    • To develop and validate a method for contrast-noise-ratio (CNR) enhancement.

    Main Methods:

    • Acquisition of energy-resolved x-ray dark-field images using a 16-energy-channel photon-counting pixel detector.
    • Utilized a 1 mm thick Cadmium Telluride (CdTe) sensor within a Talbot-Lau x-ray interferometer.
    • Experimental validation of a proposed CNR enhancement method.

    Main Results:

    • Achieved a contrast-noise-ratio (CNR) improvement by a factor of 1.14.
    • Demonstrated the effectiveness of energy-resolving detectors in enhancing dark-field image quality.
    • The observed CNR improvement is equivalent to a potential 23% reduction in radiation dose.

    Conclusions:

    • Energy-resolving pixel detectors significantly enhance dark-field image quality in grating-based XPCi.
    • The developed CNR enhancement method is experimentally validated and effective.
    • This technique holds potential for dose reduction in XPCi applications, improving patient safety.