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Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection
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[Vaccination is not always sufficient to prevent vertical transmission of hepatitis B virus]

Erik H J C Buster1, Robert A de Man

  • 1Erasmus MC, afd. Maag-Darm-Leverziekten, Rotterdam.

Nederlands Tijdschrift Voor Geneeskunde
|October 17, 2014
PubMed

Routine screening of pregnant women for infection with hepatitis B virus and active-passive immunization of newborns resulted in a dramatic decline in vertical transmission of hepatitis B. A recent study in the Annals of Internal Medicine identified factors associated with failure of active-passive immunization of newborns from hepatitis B virus infected mothers. A further decline in the incidence of vertical transmission of hepatitis B virus may be expected when referral for and initiation of antiviral therapy in the last trimester of pregnancy for selected patients can be optimized.

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