Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Eaten to death.

Charles Nelson1, Eric H Baehrecke

  • 1Department of Cancer Biology, University of Massachusetts Medical School, Worcester, MA, USA.

The FEBS Journal
|October 18, 2014
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The pyruvate transporter hermes regulates autophagy and health by modulating ROS production.

Cell reports·2026
Same author

Cholesterol transfer proteins promote Atg-independent ER clearance by lysosomes.

Cell reports·2026
Same author

Multi-dimensional regulation of LIN-28 temporal expression dynamics in the C. elegans heterochronic gene cascade.

Development (Cambridge, England)·2026
Same author

Early differential impact of MeCP2 mutations on functional networks in Rett syndrome patient-derived human cortical organoids.

Nature communications·2026
Same author

Cupping therapy for fibromyalgia: A scoping review of proposed mechanisms.

Journal of bodywork and movement therapies·2026
Same author

Delivering malaria services during the COVID-19 pandemic: challenges and lessons from an international non-governmental organisation.

International health·2026
Same journal

Nephronophthisis: Current clinical spectrum and molecular pathogenesis.

The FEBS journal·2026
Same journal

PDC1 deficiency results in 2-deoxyglucose sensitivity through inhibition of Pdc2 activity in yeast.

The FEBS journal·2026
Same journal

Epigenetic regulation of the hepcidin gene expression in hepatoma cells.

The FEBS journal·2026
Same journal

Loss of Ambp ameliorates steatosis progression by activating PPARα signaling in zebrafish.

The FEBS journal·2026
Same journal

Varying susceptibility of subpopulations along the epithelial-mesenchymal spectrum to undergo EMT.

The FEBS journal·2026
Same journal

ALOX15 links lipid metabolism to receptor trafficking in platelet activation.

The FEBS journal·2026
See all related articles

Macro-autophagy (autophagy) degrades cellular components. This review explores autophagy's unclear role in physiological cell death and its implications for understanding cellular destruction.

Area of Science:

  • Cell Biology
  • Molecular Biology
  • Physiology

Background:

  • Macro-autophagy (autophagy) is a cellular process for degrading cytoplasmic material via the lysosome.
  • Autophagy is recognized for its roles in cellular stress, infection response, and survival.
  • The specific involvement of autophagy during cell death processes is not well understood.

Purpose of the Study:

  • To review the current knowledge on the role of autophagy in physiological cell death.
  • To discuss the implications of understanding autophagy's function in cellular destruction.

Main Methods:

  • Literature review of existing research on autophagy and cell death.
  • Synthesis of findings regarding autophagy's involvement in various cell death pathways.
Keywords:
ATG genesapoptosisautophagycell deathnecrosis

Related Experiment Videos

Main Results:

  • Autophagy plays multifaceted roles in physiological cell death, which are context-dependent.
  • Evidence suggests autophagy can promote or inhibit cell death depending on the specific cellular conditions and stimuli.

Conclusions:

  • Clarifying autophagy's role in cell death is crucial for understanding fundamental cellular processes.
  • Further research into autophagy-mediated cell death could have implications for disease treatment and cellular biology.