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Updated: Apr 22, 2026

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Thromboembolism and bleeding in bladder cancer.

Joseph J Fantony, Brant A Inman

    Oncology (Williston Park, N.Y.)
    |October 18, 2014
    PubMed
    Summary

    Bladder cancer patients often experience both bleeding and clotting issues. This review examines these dual risks, particularly around surgery, and suggests management strategies.

    Area of Science:

    • Oncology
    • Hematology

    Background:

    • Bladder cancer presents with hematuria, often involving significant bleeding.
    • Simultaneously, patients with bladder cancer exhibit a propensity for aberrant clotting.
    • Managing these dual hemostatic challenges is critical in patient care.

    Purpose of the Study:

    • To review the literature on simultaneous bleeding and venous thromboembolism in bladder cancer patients.
    • To formulate a management approach for these concomitant hemostatic issues.
    • To provide direction for future research in this area.

    Main Methods:

    • Literature review focusing on bleeding and venous thromboembolism in bladder cancer.
    • Analysis of pre- and post-operative periods.
    • Formulation of a general management strategy.

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    Main Results:

    • Bladder cancer is associated with simultaneous risks of significant hemorrhage and clotting.
    • Both bleeding and venous thromboembolism are key considerations in the management of bladder cancer patients.
    • Further investigation is needed to balance these risks.

    Conclusions:

    • Physicians must recognize and address the biochemical changes leading to dual hemostatic risks in bladder cancer.
    • Effective management requires awareness of both bleeding and clotting predispositions.
    • Further studies are essential to mitigate and balance the risks of hemorrhage and thrombosis.