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High-intensity training following lung cancer surgery: a randomised controlled trial
E Edvardsen1, O H Skjønsberg2, I Holme3
1Department of Pulmonary Medicine, Oslo University Hospital, Oslo, Norway Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.
Thorax
|October 18, 2014
Summary
High-intensity exercise training significantly improved physical fitness, muscle mass, and quality of life in lung cancer patients after surgery. This approach is well-tolerated and beneficial for recovery.
Area of Science:
- Oncology
- Exercise Physiology
- Rehabilitation Medicine
Background:
- Lung cancer patients often experience deconditioning and reduced physical fitness.
- Lung resection surgery further exacerbates physical decline, impacting daily functioning.
Purpose of the Study:
- To evaluate the effectiveness of high-intensity endurance and strength training in improving physical capacity and quality of life in patients post-lung cancer surgery.
Main Methods:
- A single-blind randomized controlled trial involving 61 patients undergoing lung cancer surgery.
- Intervention group: 20 weeks of high-intensity endurance and strength training (60 min, 3x/week) starting 5-7 weeks post-surgery.
- Control group: standard postoperative care. Primary outcome: change in peak oxygen uptake.
Main Results:
- The exercise group showed significant improvements in peak oxygen uptake, carbon monoxide transfer factor (Tlco), leg press strength (1RM), chair stand, stair run, and total muscle mass compared to controls.
- Quality of life scores (SF-36 physical and mental component summaries) were significantly higher in the exercise group.
Conclusions:
- High-intensity endurance and strength training is well-tolerated in patients after lung cancer surgery.
- This exercise regimen leads to clinically significant improvements in cardiorespiratory fitness, muscular strength, body composition, functional capacity, and quality of life.
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