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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

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Practical implications of the migraine cardio- and cerebrovascular association: unmet needs of patients

Hans-Christoph Diener1, Tobias Kurth2, Dagny Holle3

  • 1Department of Neurology and Headache Center, University Hospital Essen, Germany hans.diener@uni-duisburg-essen.de.

Cephalalgia : an International Journal of Headache
|October 18, 2014
PubMed

Insights

Migraine patients with cardiovascular disease require careful medication choices, as some common migraine drugs are contraindicated. This highlights an unmet need for safe and effective treatments in this comorbid population.

Area of Science:

  • Neurology
  • Cardiology
  • Pharmacology

Background:

  • Migraine is increasingly linked to cardiovascular disease and stroke.
  • Comorbid migraine and cardiovascular/cerebrovascular disease presents therapeutic challenges.

Purpose of the Study:

  • To review medical therapy modifications for patients with comorbid migraine and cardio-cerebrovascular disorders.
  • To identify contraindications for migraine treatments in these patients.

Main Methods:

  • Literature review of publications from the last 15 years.
  • Analysis of medical therapy modifications in patients with comorbid conditions.

Main Results:

  • Ergots and triptans are contraindicated for migraine attacks in some patients.
  • Aspirin and NSAIDs are contraindicated in patients with cerebral bleeding.
  • Certain acute migraine treatments are contraindicated in patients with coronary heart disease.

Conclusions:

  • There is a significant unmet need for safe and effective migraine treatments in patients with cardiovascular and cerebrovascular disease.
  • Therapeutic strategies must consider the contraindications of various migraine medications.
Abstract

Keywords:
MigraineTIAcardiovascularcerebral hemorrhagemedical therapystroke

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