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Related Concept Videos

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The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
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The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein...
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Keloids and hypertrophic scars: characteristic vascular structures visualized by using dermoscopy.

Min Gun Yoo1, Il-Hwan Kim1

  • 1Department of Dermatology, Korea University College of Medicine, Seoul, Korea.

Annals of Dermatology
|October 18, 2014
PubMed
Summary

Dermoscopy reveals distinct vascular patterns in keloids versus hypertrophic scars. This finding aids dermatologists in differentiating these excessive scarring conditions, improving treatment selection.

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Blood vesselsDermoscopyHypertrophic scar (hypertrophic cicatrix)Keloid

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Area of Science:

  • Dermatology
  • Pathology
  • Medical Imaging

Background:

  • Keloids and hypertrophic scars are forms of excessive scarring.
  • Distinguishing between keloids and hypertrophic scars is clinically challenging due to similar morphology.
  • Accurate differentiation is crucial as therapeutic approaches differ for each condition.

Purpose of the Study:

  • To investigate and compare the clinical and dermoscopic features of keloids and hypertrophic scars.
  • To identify key diagnostic markers that assist dermatologists in differentiating these scar types.
  • To evaluate the role of vascular structures in distinguishing keloids from hypertrophic scars.

Main Methods:

  • Clinical examination and digital dermoscopy were performed on 41 keloid and hypertrophic scar lesions.
  • Patients with keloids and hypertrophic scars were included in the study.
  • Vascular structures within the lesions were meticulously evaluated using dermoscopy.

Main Results:

  • Dermoscopy identified vascular structures in 90% of keloid lesions, compared to only 27% of hypertrophic scars.
  • Common vascular patterns in keloids included arborizing (52%), linear irregular (33%), and comma-shaped (15%).
  • The frequency and distribution of these vascular structures differed significantly between keloids and hypertrophic scars (p<0.001).

Conclusions:

  • Dermoscopic examination of vascular structures shows a strong association with keloids.
  • The presence and type of vascular structures observed via dermoscopy are valuable for differentiating keloids from hypertrophic scars.
  • Dermoscopy offers a clinically useful tool for improving diagnostic accuracy in excessive scarring.