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Macroautophagy and the oncogene-induced senescence

Daniel Grasso1, Maria I Vaccaro1

  • 1Institute of Biochemistry and Molecular Medicine, National Council for Scientific and Technological Research, Department of Pathophysiology, School of Pharmacy and Biochemistry, University of Buenos Aires , Buenos Aires , Argentina.

Frontiers in Endocrinology
|October 18, 2014
PubMed
Summary

Oncogene-induced senescence acts as a tumor suppressor. This review explores the role of macroautophagy in senescence and its potential as a future cancer therapy target.

Keywords:
autophagycanceroncogene-induced senescencesenescencetumor suppression mechanisms

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