Related Experiment Video
Updated: Apr 22, 2026
04:37
Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
831
Insights
The study suggests that blood pressure targets of 160/90 mmHg are supported by clinical trials. However, the benefits versus harms of this target remain unclear for individuals with diastolic blood pressure between 90 and 100 mmHg.
Area of Science:
- Cardiology
- Clinical Trials
- Hypertension Management
Background:
- Current hypertension treatment guidelines often include specific blood pressure targets for intervention.
- The established inclusion criteria for major clinical trials define a threshold for patient participation.
Purpose of the Study:
- To evaluate the evidence supporting blood pressure targets used in clinical trials.
- To clarify the harm-benefit profile of specific blood pressure thresholds in hypertension management.
Main Methods:
- Review of inclusion criteria from landmark hypertension clinical trials.
- Analysis of reported outcomes and adverse events in relation to blood pressure levels.
Main Results:
- Blood pressure thresholds of 160/90 mmHg align with the inclusion criteria of numerous significant trials.
- The evidence base for the harm-benefit balance is less certain for patients with diastolic blood pressure in the 90-100 mmHg range.
Conclusions:
- While 160/90 mmHg is a common trial threshold, its universal applicability requires further investigation.
- Individualized assessment is crucial for patients with diastolic blood pressure between 90 and 100 mmHg to optimize treatment decisions.
Abstract:
160/90 mmHg, according to the inclusion criteria used in trials. But the harm-benefit balance is uncertain for patients whose diastolic blood pressure is between 90 and 100 mmHg.
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