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Updated: Apr 21, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
[Complications associated with catheter ablation of atrial fibrillation]
Stephan Zellerhoff1, Roland R Tilz, Lars Eckardt
1Abteilung für Rhythmologie, Department für Kardiologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, Gebäude A1, 48149, Münster, Deutschland, Stephan.Zellerhoff@ukmuenster.de.
Insights
Catheter ablation for atrial fibrillation (AF) is increasingly common. Acute complications occur in 6.3% of procedures, with cardiac issues most frequent, and risks increase with age, female gender, and less experienced centers.
Area of Science:
- Cardiology
- Medical Device Technology
- Public Health
Context:
- Catheter ablation is a crucial treatment for atrial fibrillation (AF), with rising global procedure volumes.
- Real-world complication data is now available through International Classification of Diseases (ICD) codes, supplementing earlier survey and single-center reports.
- Understanding complication trends and risk factors is vital for improving patient safety in AF ablation.
Purpose:
- To analyze the incidence and trends of acute complications associated with catheter ablation for atrial fibrillation using ICD code-based data.
- To identify specific types of complications and associated risk factors, including patient demographics and procedural experience.
- To provide a comprehensive overview of real-world complication rates in AF ablation.
Summary:
- The overall acute complication rate for catheter ablation in atrial fibrillation is 6.3%, showing a slight increase over the past decade.
- Cardiac complications are the most common, followed by vascular, respiratory, and neurological issues.
- Advanced age (over 80), female gender, and less experienced operators/hospitals are identified as risk factors for higher complication rates.
Impact:
- This analysis provides critical insights into the safety profile of contemporary catheter ablation for AF.
- Findings can inform clinical practice guidelines, patient selection, and training programs to mitigate risks.
- Real-world data on complications aids in setting benchmarks and driving quality improvement initiatives in electrophysiology.
Abstract:
The past years catheter ablation has gained significant importance in the treatment of atrial fibrillation (AF), hence procedure numbers have risen worldwide. Initially, data concerning complications were only available through surveys and single center reports but international classification of diseases (ICD) code-based data have recently been published representing real world conditions. The rate of overall acute complications is 6.3 % and has risen slightly in the past 10 years whereby cardiac complications occurred most frequently, followed by vascular, respiratory and neurological complications. Risk factors for a higher complication rate are advanced age (> 80 years), female gender and less experienced investigators and hospitals.
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