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First-trimester crown-rump length affects birth size symmetrically.

Emin Ustunyurt1, Harun Simsek1, Barış Korkmaz1

  • 1a Department of Obstetrics and Gynecology , Bursa Şevket Yılmaz Research and Education Hospital , Bursa , Turkey and.

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Summary

First-trimester crown-rump length (CRL) impacts newborn size. Smaller CRL is linked to lower birth weight, while larger CRL correlates with increased birth weight and length, without altering ponderal index.

Keywords:
Birthweightcrown-rump lengthfirst trimesterponderal index

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Area of Science:

  • Perinatal Medicine
  • Fetal Development
  • Neonatal Outcomes

Background:

  • First-trimester ultrasound measurements are crucial for assessing fetal growth.
  • Crown-rump length (CRL) is a key indicator of early fetal development.

Purpose of the Study:

  • To examine the association between first-trimester crown-rump length (CRL) and neonatal outcomes.
  • To determine if CRL variations predict birth weight, length, and head circumference.

Main Methods:

  • Analysis of 999 singleton pregnancies with first-trimester CRL measurements.
  • Exclusion of pregnancies with medical issues, abnormal menstrual history, or chromosomal/congenital abnormalities.
  • Categorization of participants into groups based on CRL: smaller-than-expected, normal, and larger-than-expected.

Main Results:

  • Higher incidence of low birth weight in the smaller CRL group compared to the larger CRL group.
  • Increased rates of macrosomic (large for gestational age) infants in the larger CRL group.
  • Neonates in the larger CRL group had greater birth length and head circumference.

Conclusions:

  • First-trimester fetal growth patterns significantly influence neonatal size.
  • CRL is a reliable predictor of birth weight and length, but not ponderal index.
  • Early growth trajectory affects symmetric development of neonatal anthropometrics.