Related Experiment Video

Updated: Apr 21, 2026

A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta
11:44

A Primary Human Trophoblast Model to Study the Effect of Inflammation Associated with Maternal Obesity on Regulation of Autophagy in the Placenta

Published on: September 27, 2017

11.2K

Effects of maternal obesity on antenatal, perinatal and neonatal outcomes

Muhittin Eftal Avcı1, Fatih Şanlıkan2, Mehmet Çelik2

  • 1a Department of Perinatology , Tepecik Training and Research Hospital , Yenişehir , Izmir , Turkey .

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|October 21, 2014
PubMed

Insights

Maternal obesity significantly increases the risk of pregnancy complications, leading to adverse outcomes for both mother and baby. This study highlights the critical impact of obesity on perinatal health.

Area of Science:

  • Perinatal Medicine
  • Obstetrics
  • Public Health

Background:

  • Maternal obesity is a growing concern impacting pregnancy.
  • Obesity poses significant risks to both maternal and fetal well-being during the perinatal period.

Purpose of the Study:

  • To investigate the complications associated with maternal obesity during pregnancy.
  • To analyze the effects of obesity on maternal and fetal outcomes.

Main Methods:

  • A cohort of 931 pregnant women was studied between March 2012 and March 2013.
  • Participants were categorized into underweight, normal weight, overweight, and obese groups based on Body Mass Index (BMI).

Main Results:

  • Obese women experienced higher rates of pregnancy-induced hypertension, gestational diabetes, cesarean delivery, and postpartum infections.
  • Infants born to obese mothers had increased risks of preterm birth, perinatal mortality, low APGAR scores, NICU admission, hypoglycemia, and macrosomia.
  • Low birth weight was more prevalent in underweight mothers compared to other BMI categories.

Conclusions:

  • Maternal obesity is a significant risk factor for increased maternal-fetal morbidity and mortality.
  • Addressing maternal obesity is crucial for improving perinatal health outcomes.
Abstract

Keywords:
Body mass indexobesitypregnancy outcomes

More Related Videos

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development05:44

Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development

Published on: May 17, 2024

1.2K
Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes03:19

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

875

Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.9K
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
1.5K
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.8K
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
58
Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.1K
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
353