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Protocol for Long Duration Whole Body Hyperthermia in Mice
Published on: August 25, 2012
[Immune status of patients with malignant melanoma during combined therapy including local ultra-high frequency
Immune status was evaluated in patients with clinical stage I malignant melanoma randomized to receive either preoperative irradiation (27 Gy) alone or in combination with local microwave hyperthermia (before or after it). Mononuclear, total T-lymphocyte, T-helper, T-suppressor, B-lymphocyte and blood-immune complex levels were assayed. The analysis of immunologic parameters dynamics pointed to beneficial changes occurring in immunoregulating T-lymphocytes in patients receiving hyperthermia as a component of combined treatment.
Immune status was evaluated in patients with clinical stage I malignant melanoma randomized to receive either preoperative irradiation (27 Gy) alone or in combination with local microwave hyperthermia (before or after it). Mononuclear, total T-lymphocyte, T-helper, T-suppressor, B-lymphocyte and blood-immune complex levels were assayed. The analysis of immunologic parameters dynamics pointed to beneficial changes occurring in immunoregulating T-lymphocytes in patients receiving hyperthermia as a component of combined treatment.
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