Jove
Visualize
Contact Us

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.6K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.6K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of Infected, Non-Responsive Atopic Dermatitis in a Romanian Center.

Journal of clinical medicine·2026
Same author

Comparative Effects of Donepezil and Tacrine on Recall-Related Exploratory Behavior in a Subacute Lipopolysaccharide-Induced Neuroinflammatory Model of Cognitive Impairment.

Biomedicines·2026
Same author

Venlafaxine as Monotherapy and in Combination Regimens in Acute Rodent Nociception Experimental Models: A Review.

International journal of molecular sciences·2026
Same author

Behavioral Paradigms and Methodological Variability in Aluminum Chloride-Induced Rat Models of Alzheimer's Disease: A Structured Review.

Biology·2026
Same author

Differential Effects of Donepezil and Tacrine on Recall-Phase Exploration in a Trihexyphenidyl-Induced Cholinergic Impairment Y-Maze Model.

Biomedicines·2026
Same author

Delayed Ischemic Hepatocellular Injury Following Cemented Total Hip Arthroplasty: A Case Report Within the Spectrum of Bone Cement Implantation Syndrome.

Life (Basel, Switzerland)·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Apr 21, 2026

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

846

Correlation between corneal thickness and optic disc morphology in normal tension glaucoma using modern technical

Laurenţiu Coman1, Monica Costescu, Mihail Alecu

  • 1Department of Physiology, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania; laurentiucmn@yahoo.com.

Romanian Journal of Morphology and Embryology = Revue Roumaine De Morphologie Et Embryologie
|October 21, 2014
PubMed
Summary

Central corneal thickness (CCT) is linked to optic disc appearance in normal tension glaucoma (NTG). The strongest connection was found in the generalized enlargement type of optic disc morphology.

More Related Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

7.7K
Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software
08:57

Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software

Published on: September 4, 2021

3.6K

Related Experiment Videos

Last Updated: Apr 21, 2026

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

846
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

7.7K
Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software
08:57

Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software

Published on: September 4, 2021

3.6K

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Corneal Biomechanics

Background:

  • Normal tension glaucoma (NTG) is a progressive optic neuropathy.
  • Understanding factors influencing optic disc damage in NTG is crucial for diagnosis and management.
  • Central corneal thickness (CCT) is a known factor in intraocular pressure assessment.

Purpose of the Study:

  • To investigate the relationship between central corneal thickness (CCT) and optic disc morphology in patients with normal tension glaucoma (NTG).
  • To determine if CCT correlates with specific patterns of optic disc changes in NTG.

Main Methods:

  • Patients diagnosed with NTG underwent comprehensive eye examinations.
  • Optic disc imaging was performed using the Heidelberg Retina Tomograph II (HRT II).
  • Corneal pachymetry was conducted using ultrasound to measure CCT.
  • Optic discs were classified into four morphological types: generalized enlargement (GE), myopic glaucomatous (MY), focal ischemic (FI), and senile sclerotic (SS).

Main Results:

  • A correlation analysis was performed between CCT and optic disc morphological parameters obtained via HRT II.
  • Statistical tests (multiple comparison, post hoc) were used to assess group differences.
  • The strongest correlation between CCT and HRT II imaging parameters was observed in the generalized enlargement (GE) type of optic disc.

Conclusions:

  • Central corneal thickness shows a significant relationship with optic disc morphology in normal tension glaucoma.
  • The generalized enlargement (GE) type of optic disc morphology exhibits the strongest correlation with CCT.
  • These findings may contribute to a better understanding of glaucoma pathophysiology and risk stratification.