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Inhibin alpha-subunit, Melan A and MNF116 in pheochromocytomas
Diana Păun1, Marius Cristian Neamţu, Elena Taina Avramescu
1"Prof. Dr. Dorin Hociota" Institute of Phono-Audiology and ENT Functional Surgery, Bucharest, Romania; madalina.georgescu@gecad.com.
Aim:
The aim of this study was to make immunohistochemical analyses with Inhibin alpha-subunit, Melan A and MNF116 (pan-Cytokeratin antibody) in pheochromocytomas, because immunohistochemistry is useful for the distinction between adrenal tumors.
Patients And Methods:
We used 20 patients with pheochromocytomas submitted to laparoscopic (n=19) or classical (n=1) surgery and we have explored immuno-staining with Inhibin alpha-subunit, Melan A and MNF116 in these tumors. This can be helpful when we cannot make the distinction between adrenal tumors.
Results:
Pheochromocytomas did not stain with Inhibin alpha-subunit, Melan A and MNF116.
Conclusions:
In our study, Inhibin alpha-subunit, Melan A and MNF116 were not sensitive for pheochromocytomas.
