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Updated: Apr 21, 2026

The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
Maternal ABO blood group and stillbirth: a prospective cohort investigation
Objective:
To determine whether maternal ABO blood group is associated with risk of stillbirth.
Study Design:
Prospective cohort. Risk of stillbirth among women of blood group A, B and AB was compared to that of women with group O by logistic regression and survival analysis.
Results:
There were 1,018 stillbirths in 52,605 pregnancies (19.4 per thousand). Stillbirths occurred in 19.2/ 1,000 pregnancies in group O, 19.8/1,000 pregnancies in group A (race-adjusted odds ratio [OR] vs. group O of 1.1, 95% confidence interval [CI] 0.9-1.2), 19.4/1,000 to group B (race-adjusted OR vs. group O of 1.0, 95% CI 0.8-1.2), and 17.2/1,000 pregnancies in group AB (race-adjusted OR vs. group O of 0.9, 95% CI 0.6-1.2) women. Survival analysis, accounting for varying times at entry to prenatal care, produced similar results. Results were similar for singleton births, stillbirths < 24 weeks' and > or = 24 weeks' gestation, and antepartum and intrapartum stillbirths considered separately.
Conclusion:
Maternal ABO blood group was not associated with stillbirth.
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