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Updated: Apr 21, 2026
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Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain
Published on: February 22, 2019
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Assessment of knee joint pain in experimental rodent models of osteoarthritis
Margaret J Piel1, Jeffrey S Kroin, Hee-Jeong Im
1Comparative Medicine Consultants, Chicago, IL, 60631, USA.
Methods in Molecular Biology (Clifton, N.J.)
|October 22, 2014
Abstract:
Pain assessment in animal models of osteoarthritis is integral to interpretation of a model's utility in representing the clinical condition, and enabling accurate translational medicine. Here we describe two methods for behavioral pain assessments available for use in animal models of experimental osteoarthritic pain: Von Frey filaments and spontaneous activity monitoring.
