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Related Experiment Video

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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Is undertransfusion a problem in modern clinical practice?

Stephen Hibbs1,2, David Miles3, Julie Staves3

  • 1Oxford University Clinical Academic Graduate School, Oxford, UK.

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This summary is machine-generated.

This study found no evidence of inappropriate undertransfusion in patients with low hemoglobin or platelet counts. Developing monitoring systems for undertransfusion is recommended alongside efforts to reduce overtransfusion.

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Area of Science:

  • Hematology
  • Transfusion Medicine
  • Clinical Pathology

Background:

  • Efforts to reduce inappropriate blood product transfusion are ongoing.
  • Monitoring for underutilization of transfusions in eligible patients is also necessary.

Purpose of the Study:

  • To develop a method for monitoring undertransfusion of blood products.
  • To assess the prevalence of undertransfusion in clinical practice.

Main Methods:

  • Identified patients with hemoglobin < 6 g/dL or platelet count < 10 × 10(9)/L.
  • Excluded patients transfused within 72 hours of low readings.
  • Reviewed records of non-transfused patients against justification criteria.

Main Results:

  • 63 eligible hemoglobin and 130 eligible platelet counts were identified in 93 patients.
  • 36 patients were not transfused within 72 hours of low readings.
  • Most non-administrations (28/36) were justified by repeat testing or medical inappropriateness; no unjustified undertransfusions were found.

Conclusions:

  • This study did not identify inappropriate undertransfusion.
  • Monitoring systems for undertransfusion should be developed, similar to those for overtransfusion.