Related Experiment Video
Updated: Apr 21, 2026

Production and Testing of Antimicrobial Peptides and Their Mimics
Published on: April 10, 2026
Antimicrobial γ-AApeptides (WO2013112548): a patent evaluation
Peng Teng1, Haifan Wu, Lili Lin
1University of South Florida, Department of Chemistry , 4202 E. Fowler Ave, Tampa, FL 33620 , USA +1 813 974 9506 ; +1 813 974 3203 ; jianfengcai@usf.edu.
Abstract:
The patent application WO2013112548 claims a new class of peptidomimetics - γ-AApeptides with potent and broad-spectrum antimicrobial activity. These γ-AApeptides are active against both Gram-positive and Gram-negative bacteria, including medicinally relevant drug-resistant pathogens. They are believed to exert bactericidal function by mimicking the membrane disruption mechanism of host-defense peptides. As such, they may provide an alternative approach for antimicrobial development combating antibiotic resistance.
Related Concept Videos
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Inhibitors of Gram-positive Cell Wall Synthesis
Antimicrobial Effectiveness
Inhibitors of Bacterial Protein Synthesis
Antifungal Agents
Pharmaceutical Alternatives: Stability-Related Therapeutic Nonequivalence

