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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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CD4+ CD56+ Hematodermic Neoplasm Without Cutaneous Involvement.

Seema Sharma1, Chanchal Rana1

  • 1Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Science, Type 5B/13, SGPGIMS, Raibareli Road, Lucknow, 226014 Uttar Pradesh India.

Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion
|October 22, 2014
PubMed
Summary
This summary is machine-generated.

CD4+/CD56+ hematodermic neoplasm, an aggressive cancer, typically affects the skin. This case highlights a rare presentation without skin lesions, emphasizing the need for broader diagnostic considerations.

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Area of Science:

  • Hematology
  • Oncology
  • Dermatopathology

Background:

  • CD4+/CD56+ hematodermic neoplasm is a rare, aggressive hematologic malignancy.
  • It characteristically presents with skin lesions, often progressing to lymph node, bone marrow, and leukemic phases.

Observation:

  • A case of CD4+/CD56+ hematodermic neoplasm is presented in an elderly male.
  • The patient exhibited generalized weakness, with investigations revealing the neoplasm.

Findings:

  • A key finding was the absence of cutaneous involvement, a highly unusual presentation.
  • Bone marrow and peripheral blood were involved, deviating from the typical skin-first manifestation.

Implications:

  • This case underscores the importance of considering CD4+/CD56+ hematodermic neoplasm even without skin lesions.
  • It suggests that hematologic evaluation is crucial for diagnosing atypical presentations of this aggressive tumor.