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Autoimmune haemolytic anaemia emerging during Campath treatment in a patient with CD5 negative chronic lymphocytic
Paul R J Ames1, Darren Aw2, Mervin G Rainey2
1Department of Haematology, Inverclyde Royal Hospital, Larkfield Road, Greenock, PA16 0XN Scotland, UK ; Centre for Sports and Exercise Medicine, William Harvey Research Institute, Queen Mary University of London, 327 Mile End Rd, London, E1 4NS UK.
Abstract:
Campath is being employed for the treatment of autoimmune haemolytic anemia (AIHA) whether or not associated to B cell chronic lymphoid leukaemia (CLL). CD5 negative CLL is relatively uncommon and runs an indolent course. We report a CD5 negative CLL patient who developed AIHA associated with cytomegalovirus infection reactivation whilst on treatment with Campath for progressive disease.
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